Trevor N. Brown

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CV of Trevor N. Brown


Education and Employment

Dr. Brown obtained his B.Sc. in Environmental Chemistry at Thompson Rivers University (TRU) in Kamloops, B.C., Canada. He received a cooperative education endorsement for a work term as an analytical chemist at ALS Environmental in Vancouver, and a work term as a research assistant with Nelaine Mora-Diez at TRU. He obtained his Ph.D. in Environmental Chemistry at the University of Toronto. His Ph.D. thesis, titled “Automated Methods in Chemical Risk Assessment”, was supervised by Frank Wania, at the University of Toronto Scarborough campus. After his Ph.D. he was a Postdoc at the Helmholtz Centre for Environmental Research (UFZ) in Leipzig, Germany, where he did research in the Analytical Environmental Chemistry group with Kai-Uwe Goss. He was then a Postdoc at Dalhousie University in Halifax, Canada, in the research group of Russell Boyd (retired). More recently he worked for three years as a Physical Scientist in the Department of Fisheries and Oceans Canada where he worked on modelling oil properties and the chemistry of oil spills within the Centre for Offshore Oil, Gas and Energy Research (COOGER) headed by Tom King. Right now Dr. Brown collaborates extensively with Jon Arnot, subcontracting for ARC Arnot Research and Consulting.

Publications

  1. Brown T.N.; Sangion A.; Arnot J.A. Identifying uncertainty in physical-chemical property estimation with IFSQSAR. J Cheminform 2024, 16, 65. [DOI] [Model]
  2. Zhang Z.; Sangion A.; Wang S.; Gouin T.; Brown T.N.; Arnot J.A.; Li L. Chemical Space Covered by Applicability Domains of Quantitative Structure–Property Relationships and Semiempirical Relationships in Chemical Assessments. Environ Sci Technol 2024, 58, 3386-3398. [DOI]
  3. Zhang Z.; Wang S.; Brown T.N.; Sangion A.; Arnot J.A.; Li L., Modeling sorption of environmental organic chemicals from water to soils. Water Research X 2024, 22, 100219. [DOI]
  4. Celsie A.K.D.; Parnis J.M.; Brown T.N., Metrics for estimating vapour pressure deviation from ideality in binary mixtures. SAR QSAR Environ Res 2023, 34, 943-961. [DOI]
  5. Zhang Z.; Sangion A.; Wang S.; Gouin T.; Brown T.N.; Arnot J.A.; Li L., Hazard vs. exposure: Does it make a difference in identifying chemicals with persistence and mobility concerns? Water Research 2023, 245, 120610. [DOI]
  6. Ding Y.; Hayward S.J.; Westgate J.N.; Brown T.N.; Lei Y.D.; Wania F., Legacy and current-use pesticides in Western Canadian mountain air: Influence of pesticide sales, source proximity, and altitude. Atmos Environ 2023, 308, 119882. [DOI]
  7. Arnot J.A., Toose L., Armitage J.M., Sangion A., Looky A., Brown T.N., Li L., Becker R.A., Developing an internal threshold of toxicological concern (iTTC). Journal of Exposure Science & Environmental Epidemiology, 2022, 32, 877-884. [DOI]
  8. Brown T.N., QSPRs for predicting equilibrium partitioning in solvent-air systems from the chemical structures of solutes and solvents. J. Solution Chem. 2022. [DOI] [Model]
  9. Brown T.N., Empirical regressions between system parameters and solute descriptors of polyparameter linear free energy relationships (PPLFERs) for predicting solvent-air partitioning. Fluid Phase Equilibria, 2021. 540: 113035. [DOI]
  10. Brown T.N., J.M. Armitage, and J.A. Arnot, Application of an Iterative Fragment Selection (IFS) Method to Estimate Entropies of Fusion and Melting Points of Organic Chemicals. Molecular Informatics, 2019, 38(8-9): 1800160. [DOI] [Model]
  11. Hussain B.A., Westgate J.N., Hayward S.J., Shunthirasingham C., Brown T.N., Hung H., Lei Y.D., Wania F.; Polycyclic aromatic hydrocarbons and polychlorinated biphenyls in soils and atmosphere of Western Canadian mountains: The role of source proximity, precipitation, forest cover and mountain cold-trapping. Atmosph. Environ. X, 2019, 1, 100004. [DOI]
  12. Undeman E., Brown T.N., McLachlan M.S., Wania F.; Who in the world is most exposed to polychlorinated biphenyls? Using models to identify highly exposed populations. Environ. Res. Lett., 2018, 13, 064036. [DOI]
  13. Ulrich N., Endo S., Brown T.N., Watanabe N., Bronner G., Abraham M.H., Goss K.-U., UFZ-LSER database v 3.2.1. Leipzig, Germany, Helmholtz Centre for Environmental Research-UFZ. 2017. [Model]
  14. Larisch W., Brown T.N., Goss K.U.; A toxicokinetic model for fish including multiphase sorption features. Environ. Toxicol. Chem., 2017, 36, 1538-1546. [DOI]
  15. Arp H.P.H., Brown T.N., Berger U., Hale S.E.; Ranking REACH registered neutral, ionizable and ionic organic chemicals based on their aquatic persistency and mobility. Environ. Sci. Proc. Imp., 2017, 19, 939-955. [DOI]
  16. Chen Y., Hermens J.L.M., Jonker M.T.O., Arnot J.A., Armitage J.M., Brown T.N., Nichols J.W., Fay K.A., Droge S.T.J.; Which molecular features affect the intrinsic hepatic clearance rate of ionizable organic chemicals in fish? Environ. Sci. Technol., 2016, 50, 12722-12731. [DOI]
  17. Brown T.N., Armitage J.M., Egeghy P., Kircanski I., Arnot J.A.; Dermal permeation data and models for the prioritization and screening-level exposure assessment of organic chemicals. Environ. Int., 2016, 94, 424-435. [DOI]
  18. McLachlan M.S., Kierkegaard A., Radke M., Sobek A., Malmvärn A., Alsberg T., Arnot J.A., Brown T.N., Wania F., Breivik K., Xu S.; Using model-based screening to help discover known environmental contaminants. Environ. Sci. Technol., 2014, 48, 7264-7271. [DOI]
  19. Arnot J.A., Brown T.N., Wania F.; Estimating screening-level organic chemical half-lives in humans. Environ. Sci. Technol., 2014, 48, 723-730. [DOI] [Model]
  20. Brown T.N.; Predicting hexadecane-air equilibrium partition coefficients (L) with a group contribution approach constructed from high-quality data. SAR QSAR Environ. Res., 2014, 25, 51-71. [DOI] [Model]
  21. Zhang X., Brown T.N., Ansari A., Yeun B., Kitaoka K., Kondo A., Lei Y.D., Wania F.; Effect of wind on the chemical uptake kinetics of a passive air sampler. Environ. Sci. Technol., 2013, 47, 7868-7875. [DOI]
  22. Endo S., Brown T.N., Goss K.-U.; General model for estimating partition coefficients to organisms and their tissues using the biological compositions and polyparameter linear free energy relationships. Environ. Sci. Technol., 2013, 47, 6630-6639. [DOI]
  23. Goss K.-U., Brown T.N., and Endo S.; Elimination half-life as a metric for the bioaccumulation potential of chemicals in aquatic and terrestrial food chains. Environ. Toxicol. Chem. 2013, 32, 1663-1671. [DOI]
  24. Armitage J.M., Choi S.-D., Meyer T., Brown T.N., Wania F.; Exploring the role of shelf sediments in the Arctic Ocean in determining the Arctic contamination potential of neutral organic contaminants. Environ. Sci. Technol. 2013, 47, 923-931. [DOI]
  25. Arnot J.A., Brown T.N., Wania F., Breivik K., McLachlan M.S.; Prioritizing Chemicals and Data Requirements for Screening-Level Exposure and Risk Assessment. Environ. Health Perspect. 2012, 120, 1565-1570. [DOI]
  26. Brown T.N., Arnot J.A., and Wania F.; Iterative Fragment Selection: A Group Contribution Approach to Predicting Fish Biotransformation Half-Lives. Environ. Sci. Technol. 2012, 46, 8253-8260. [DOI] [Model]
  27. Breivik K., Arnot J.A., Brown T.N., McLachlan M.S., Wania F.; Screening organic chemicals in commerce for emissions in the context of environmental and human exposure. J. Environ. Monit., 2012, 14, 2028-2037. [DOI]
  28. Undeman E., Brown T.N., Wania F., McLachlan M.S.; The Susceptibility of Human Populations to Environmental Exposure to Organic Contaminants. Environ. Sci. Technol. 2010, 44, 6249-6255. [DOI]
  29. Zhang X., Brown T.N., Wania F., Heimstad E.S., Goss K.-U.; Assessment of Chemical Screening Outcomes Based on Different Partitioning Property Estimation Methods. Environ. Int. 2010, 36, 514-520. [DOI]
  30. Brown T.N. and Wania F.; Development and Exploration of an Organic Contaminant Fate Model Using Poly-Parameter Linear Free Energy Relationships. Environ. Sci. Technol. 2009, 43, 6676-6683. [DOI]
  31. Brown T.N. and Wania F.; Screening Chemicals for the Potential to be Persistent Organic Pollutants: A Case Study of Arctic Contaminants. Environ. Sci. Technol. 2008, 42, 5202-5209. [DOI]
  32. Brown T.N. and Mora-Diez N.; Computational determination of aqueous pKa values of protonated benzimidazoles (part 1). J. Phys. Chem. B 2006, 110, 9270-9279. [DOI]
  33. Brown T.N. and Mora-Diez N.; Computational determination of aqueous pKa values of protonated benzimidazoles (part 2). J. Phys. Chem. B 2006, 110, 20546-20554. [DOI]